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Randomized controlled trial assessing the effects of xylazine sedation in 2-to 6-week-old dairy calves disbudded with a cautery iron

Authors: Cassandra N Reedman, Todd F Duffield, Trevor J DeVries, Kerry D Lissemore, Ian J Duncan, Charlotte B Winder

Publication Date: 2021/5/1

The use of local anesthesia and a nonsteroidal anti-inflammatory drug (NSAID) can reduce indicators of pain and inflammation and encourage self-rewarding behavior in calves following disbudding. Although the use of sedation may be recommended as a best practice for disbudding, there is little research in this area. The objective of this study was to evaluate the effects of xylazine sedation in conjunction with a local anesthetic and an NSAID in calves undergoing cautery disbudding. One hundred twenty-two group-housed female and male Holstein calves fed milk with automated feeders, aged 13 to 44 d, were enrolled over 9 replicates and randomly allocated to 1 of 2 treatments.

Read it here: https://www.sciencedirect.com/science/article/pii/S0022030221002642